Lamin mutation location predicts cardiac phenotype severity: combined analysis of the published literature | Open Heart
Pharmacotherapy to gene editing: potential therapeutic approaches for Hutchinson–Gilford progeria syndrome | SpringerLink
The lamin protein family | Genome Biology | Full Text
Phosphorylated Lamin A/C in the Nuclear Interior Binds Active Enhancers Associated with Abnormal Transcription in Progeria - ScienceDirect
JCI - Good news in the nuclear envelope: loss of lamin A might be a gain
What Should the Cardiologist know about Lamin Disease? | AER Journal
A novel LMNA mutation (R189W) in familial dilated cardiomyopathy: evidence for a 'hot spot' region at exon 3: a case report | Cardiovascular Ultrasound | Full Text
Normal processing of lamin A from mRNA to mature lamin A. (A) Normal... | Download Scientific Diagram
A progeria mutation reveals functions for lamin A in nuclear assembly, architecture, and chromosome organization | PNAS
Lamin - Wikipedia
Pre-Lamin A/C - Wikipedia
Frontiers | The Emerging Role of Lamin C as an Important LMNA Isoform in Mechanophenotype
The structural and gene expression hypotheses in laminopathic diseases—not so different after all | Molecular Biology of the Cell
When Lamins Go Bad: Nuclear Structure and Disease: Cell
Altered Chromosomal Positioning, Compaction, and Gene Expression with a Lamin A/C Gene Mutation | PLOS ONE
CRISPR base editor treats premature-aging syndrome | Signal Transduction and Targeted Therapy
Lamin A Truncation in Hutchinson-Gilford Progeria | Science
Lamin and the heart | Heart
Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes - ScienceDirect
David R. Liu on Twitter: "The mutation (discovered by @NIHDirector's lab in 2003) results in progerin, a toxic protein that damages nuclei. So providing more healthy LMNA is not a solution, and
Schematic of the LMNA gene and lamin A protein indicating... | Download Scientific Diagram
Cancers | Free Full-Text | Lamin A/C: Function in Normal and Tumor Cells
Comparison of lamin A, lamin C, and LA ⌬ 50 structures. ( A ) The 12... | Download Scientific Diagram
Increased expression of the Hutchinson–Gilford progeria syndrome truncated lamin A transcript during cell aging | European Journal of Human Genetics
